Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and links to their rpeorts go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html

Study Counts

Type	Study_count
Total_Studies	4213
interventional	3658
Observational	498
Registry	57

Studies over Time

```

Interventional Trials

Intervention Type

intervention_type	Study_Count
Drug	2056
Biological	228
Drug\|Other	158
Procedure	132
Other	115
Device	96
Biological\|Drug	95
Behavioral	76
Drug\|Procedure	63
Drug\|placebo	57
Radiation	51
Drug\|Radiation	42
Other\|Procedure	34
Biological\|Drug\|Other	32
Biological\|Other	29
Drug\|Procedure\|Radiation	27
Biological\|Drug\|Procedure	22
Behavioral\|Other	21
Drug\|Other\|Procedure	20
Device\|Procedure	19
Device\|Drug	17
Genetic	15
Dietary Supplement	14
Other\|Radiation	14
Procedure\|Radiation	14
Drug\|Other\|placebo	10
Drug\|Other\|Procedure\|Radiation	10
Combination Product	9
Behavioral\|Drug	8
Biological\|Drug\|Procedure\|Radiation	8
Device\|Drug\|Procedure	8
Diagnostic Test	8
Dietary Supplement\|Drug	8
Behavioral\|Other\|Procedure	7
Biological\|Drug\|Radiation	6
Biological\|Other\|Procedure	6
Device\|Other	6
Drug\|Genetic\|Other	6
Other\|Procedure\|Radiation	6
Biological\|Drug\|Other\|Procedure\|Radiation	5
Biological\|Procedure	4
Combination Product\|Drug	4
Device\|Other\|Procedure	4
Drug\|Genetic\|Other\|Procedure	4
Behavioral\|Device	3
Biological\|Drug\|Other\|Procedure	3
Biological\|placebo	3
Device\|Procedure\|Radiation	3
Device\|Radiation	3
Drug\|Genetic	3
Drug\|Other\|placebo\|Procedure	3
Behavioral\|Drug\|Other	2
Behavioral\|Drug\|placebo	2
Behavioral\|Radiation	2
Biological\|Device	2
Biological\|Device\|Drug\|Procedure	2
Biological\|Drug\|placebo	2
Biological\|Other\|Radiation	2
Device\|Drug\|Radiation	2
Dietary Supplement\|placebo	2
Drug\|Other\|Radiation	2
Drug\|placebo\|Procedure	2
Behavioral\|Device\|Drug\|placebo	1
Behavioral\|Device\|Other	1
Behavioral\|Device\|Procedure	1
Behavioral\|Dietary Supplement\|Other\|Procedure	1
Behavioral\|Drug\|Other\|placebo	1
Behavioral\|Drug\|Procedure	1
Behavioral\|placebo	1
Behavioral\|Procedure	1
Behavioral\|Procedure\|Radiation	1
Biological\|Combination Product	1
Biological\|Combination Product\|Drug\|Other	1
Biological\|Device\|Drug	1
Biological\|Device\|Drug\|Other	1
Biological\|Device\|Other	1
Biological\|Device\|placebo	1
Biological\|Device\|Procedure	1
Biological\|Dietary Supplement\|Drug\|Other\|placebo\|Procedure	1
Biological\|Genetic\|Other	1
Biological\|Genetic\|Other\|Procedure	1
Biological\|Other\|placebo	1
Biological\|Other\|Procedure\|Radiation	1
Biological\|placebo\|Procedure	1
Biological\|Radiation	1
Combination Product\|Other\|Procedure	1
Combination Product\|Procedure	1
Device\|Drug\|Genetic\|Procedure	1
Device\|Drug\|Other	1
Device\|Other\|Procedure\|Radiation	1
Device\|placebo	1
Diagnostic Test\|Drug\|Other	1
Diagnostic Test\|Drug\|Procedure	1
Diagnostic Test\|Drug\|Procedure\|Radiation	1
Diagnostic Test\|Other	1
Dietary Supplement\|Drug\|Other	1
Dietary Supplement\|Other	1
Dietary Supplement\|Other\|placebo	1
Dietary Supplement\|Other\|Procedure	1
Drug\|Genetic\|Other\|Procedure\|Radiation	1
Drug\|Genetic\|Radiation	1
Other\|placebo	1
placebo\|Procedure	1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Weekly studies for each intervention

Studies by Country

Country	Study_Count
United States	1896
China	257
NA	127
Japan	115
France	83
United States\|Canada	72
Canada	65
Korea, Republic of	62
United Kingdom	51
Germany	43
Netherlands	43
Australia	38
Italy	35
Taiwan	24
Denmark	23
Spain	17
United States\|Australia	17
United States\|United Kingdom	17
Switzerland	15
United States\|Puerto Rico	15
Belgium	14
Brazil	14
Austria	12
United States\|Spain	11
Russian Federation	10
United States\|Australia\|Canada	10
United States\|France	10
Israel	9
Sweden	9
India	8
Hong Kong	7
United States\|Italy	7
United States\|Canada\|Puerto Rico	6
United States\|Japan	6
Cuba	5
Egypt	5
Norway	5
United States\|Germany	5
United States\|Taiwan	5
Belgium\|France	4
Belgium\|Netherlands	4
Japan\|Korea, Republic of\|Taiwan	4
Netherlands\|United Kingdom	4
Singapore	4
United States\|China	4
United States\|France\|Netherlands	4
United States\|France\|United Kingdom	4
United States\|Netherlands	4
Australia\|China	3
Australia\|Korea, Republic of	3
Austria\|Belgium\|Denmark\|France\|Germany\|Netherlands\|Norway\|Switzerland\|United Kingdom	3
Czechia	3
Finland	3
France\|Spain	3
Hungary	3
Ireland	3
Japan\|Korea, Republic of	3
Mexico	3
United States\|Australia\|Canada\|New Zealand\|Puerto Rico	3
United States\|Australia\|Canada\|Puerto Rico	3
United States\|Australia\|Korea, Republic of	3
United States\|Belgium	3
United States\|Brazil	3
United States\|Germany\|Italy	3
United States\|Korea, Republic of	3
United States\|New Zealand	3
United States\|Singapore	3
United States\|Spain\|United Kingdom	3
Argentina	2
Australia\|Canada\|Korea, Republic of	2
Austria\|Belgium\|Denmark\|France\|Germany\|Greece\|Israel\|Italy\|Netherlands\|Norway\|Portugal\|Spain\|Switzerland\|United Kingdom	2
Belgium\|Denmark\|Netherlands\|United Kingdom	2
France\|Germany	2
France\|United Kingdom	2
Germany\|Norway	2
Greece	2
Iran, Islamic Republic of	2
Ireland\|Sweden	2
Italy\|Switzerland	2
Kenya	2
Poland	2
Saudi Arabia	2
Spain\|United Kingdom	2
Thailand	2
Turkey	2
United States\|Australia\|Canada\|Netherlands\|Puerto Rico\|Switzerland	2
United States\|Belgium\|France\|Spain	2
United States\|Canada\|Denmark	2
United States\|Canada\|Denmark\|France\|Italy\|Netherlands\|Spain	2
United States\|Canada\|Korea, Republic of	2
United States\|France\|Germany	2
United States\|France\|Italy\|Spain	2
United States\|France\|Spain\|United Kingdom	2
United States\|Italy\|United Kingdom	2
United States\|Netherlands\|Switzerland\|United Kingdom	2
Vietnam	2
Australia\|Belgium\|Canada\|Denmark\|Spain	1
Australia\|Belgium\|France\|Netherlands	1
Australia\|Bulgaria\|Germany\|Hungary\|India\|Israel\|Italy\|Lithuania\|Poland\|Romania\|Spain\|Taiwan\|United Kingdom	1
Australia\|Canada	1
Australia\|Canada\|France\|Korea, Republic of\|Netherlands	1
Australia\|Germany\|Italy\|Korea, Republic of\|Russian Federation\|Spain\|United Kingdom	1
Australia\|Hong Kong\|Japan\|Korea, Republic of\|Taiwan	1
Australia\|New Zealand	1
Australia\|New Zealand\|Spain	1
Austria\|Belgium\|Czechia\|Germany\|Italy\|Korea, Republic of	1
Austria\|Belgium\|Denmark\|Germany\|Lithuania\|Netherlands\|Norway\|Spain\|Sweden	1
Austria\|Bosnia and Herzegovina\|Croatia\|Germany\|India\|Italy\|Latvia\|Poland\|Romania\|Russian Federation\|Serbia\|Sweden\|Ukraine	1
Austria\|France\|Netherlands\|United Kingdom	1
Austria\|Germany\|Italy\|Korea, Republic of\|Netherlands\|Spain\|Sweden\|Switzerland\|Thailand	1
Belgium\|Brazil\|Bulgaria\|Canada\|Czech Republic\|France\|Hungary\|Italy\|Panama\|Peru\|Spain\|Sweden\|Switzerland\|United Kingdom	1
Belgium\|Canada\|Croatia\|Germany\|Portugal\|United Kingdom	1
Belgium\|Canada\|Denmark\|Netherlands\|Poland\|Spain	1
Belgium\|Canada\|Denmark\|Spain	1
Belgium\|Canada\|Germany\|United Kingdom	1
Belgium\|Denmark\|France\|Germany\|Hong Kong\|Israel\|Italy\|Korea, Republic of\|Portugal\|South Africa\|Spain\|Sweden\|Switzerland\|Taiwan\|Ukraine\|United Kingdom	1
Belgium\|Denmark\|France\|Germany\|Ireland\|Italy\|Netherlands\|Poland\|Spain\|United Kingdom	1
Belgium\|Denmark\|France\|Netherlands\|United Kingdom	1
Belgium\|Estonia\|France\|Germany\|Israel\|Italy\|Korea, Republic of\|Netherlands\|Norway\|Portugal\|Spain\|Switzerland\|United Kingdom	1
Belgium\|Finland\|Israel\|Netherlands\|Portugal\|Spain\|Switzerland\|Turkey	1
Belgium\|France\|Germany\|India\|Italy\|Netherlands	1
Belgium\|France\|Italy\|Poland\|Sweden	1
Belgium\|France\|Netherlands	1
Belgium\|France\|Spain	1
Belgium\|Germany\|Poland\|Russian Federation\|Spain	1
Belgium\|Italy\|Netherlands\|Spain\|United Kingdom	1
Belgium\|Netherlands\|United Kingdom	1
Belgium\|Spain	1
Bosnia and Herzegovina\|Croatia\|Korea, Republic of\|Spain\|Taiwan\|United Kingdom	1
Brazil\|Canada	1
Brazil\|Canada\|Cyprus\|United Kingdom	1
Canada\|Denmark	1
Canada\|Denmark\|France\|Germany\|Netherlands\|Norway\|Spain	1
Canada\|France\|Spain	1
Canada\|India	1
Canada\|United Kingdom	1
China\|Colombia\|El Salvador	1
China\|Poland\|Sweden	1
China\|Singapore\|Taiwan	1
Colombia	1
Colombia\|Germany\|Honduras\|Panama\|Taiwan	1
Costa Rica	1
Czech Republic	1
Czechia\|France\|Korea, Republic of\|Netherlands\|United Kingdom	1
Denmark\|Finland\|France\|Germany\|Norway\|Sweden	1
Denmark\|Finland\|France\|Italy\|Spain\|United Kingdom	1
Denmark\|France\|Germany\|Israel\|Korea, Republic of\|Spain\|United Kingdom	1
Denmark\|France\|Germany\|Italy\|Netherlands\|Spain\|United Kingdom	1
Denmark\|France\|Spain	1
Denmark\|Greece\|Norway\|Sweden	1
Denmark\|Norway\|Sweden	1
Denmark\|Spain	1
Finland\|Germany\|Italy\|Netherlands	1
Finland\|Germany\|Poland\|Sweden	1
France\|Germany\|Italy\|Netherlands\|Poland\|Spain\|Sweden\|United Kingdom	1
France\|Germany\|Spain\|United Kingdom	1
France\|Germany\|Switzerland	1
France\|Guadeloupe\|Martinique\|RÃ©union	1
France\|Ireland\|Israel\|Italy\|Spain	1
France\|Italy\|Japan\|Latvia\|Russian Federation\|Serbia\|South Africa\|Spain	1
France\|Italy\|Netherlands\|Spain	1
France\|Italy\|Spain	1
France\|Italy\|Spain\|United Kingdom	1
France\|Italy\|Switzerland	1
France\|Italy\|United Kingdom	1
France\|Korea, Republic of\|Spain	1
France\|Netherlands	1
France\|Netherlands\|United Kingdom	1
France\|United States\|Australia\|Austria\|Belgium\|Canada\|Germany\|Netherlands	1
France\|United States\|Belgium\|China\|Germany\|Hong Kong\|Italy\|Korea, Republic of\|Netherlands\|Singapore\|Spain\|Taiwan\|United Kingdom	1
France\|United States\|Canada\|Germany\|Israel\|Korea, Republic of\|Netherlands\|Spain\|United Kingdom	1
France\|United States\|Germany\|Italy\|Spain\|United Kingdom	1
Germany\|Greece\|Israel\|Italy\|United Kingdom	1
Germany\|Hungary	1
Germany\|Italy	1
Germany\|Italy\|Spain\|Sweden	1
Germany\|Italy\|United Kingdom	1
Germany\|Netherlands\|Sweden	1
Germany\|Netherlands\|Switzerland\|United Kingdom	1
Germany\|Netherlands\|United Kingdom	1
Germany\|Russian Federation	1
Hong Kong\|Korea, Republic of\|Malaysia\|Philippines\|Singapore\|Taiwan\|Thailand	1
Hungary\|Moldova, Republic of\|Poland\|Russian Federation	1
Ireland\|United Kingdom	1
Italy\|Poland\|United Kingdom	1
Italy\|United States\|Australia\|Canada\|Denmark\|France\|Germany\|Hungary\|Netherlands\|Poland\|Spain\|United Kingdom	1
Japan\|Australia\|Korea, Republic of	1
Japan\|Spain	1
Japan\|Taiwan	1
Japan\|United Kingdom	1
Japan\|United States\|Korea, Republic of\|Taiwan	1
Jordan	1
Korea, Republic of\|United States\|Denmark\|Hong Kong\|Spain\|Taiwan	1
Netherlands\|Spain\|Switzerland	1
Netherlands\|Spain\|United States\|France\|Germany\|Italy\|Japan\|Korea, Republic of	1
Netherlands\|Sweden\|United Kingdom	1
Netherlands\|Switzerland	1
New Zealand	1
Palestinian Territory, occupied	1
Portugal	1
Puerto Rico\|United States\|Belgium\|Bulgaria\|Czechia\|Germany\|Hungary\|Latvia\|Lithuania\|Poland\|Romania\|United Kingdom	1
Slovakia	1
South Africa	1
Switzerland\|Austria\|Belgium\|Denmark\|France\|Germany\|Greece\|Israel\|Italy\|Netherlands\|Norway\|Portugal\|Spain\|United Kingdom	1
Switzerland\|United Kingdom	1
Trinidad and Tobago	1
United States\|Argentina\|Australia\|Austria\|Belgium\|Brazil\|Canada\|Denmark\|Finland\|France\|Germany\|Greece\|Israel\|Italy\|Mexico\|Netherlands\|Poland\|Portugal\|Puerto Rico\|Russian Federation\|Spain\|Turkey\|United Kingdom	1
United States\|Argentina\|Australia\|Austria\|Belgium\|Brazil\|Canada\|France\|Germany\|Greece\|Guadeloupe\|Hungary\|Israel\|Italy\|Russian Federation\|RÃ©union\|South Africa\|Spain\|Switzerland\|Uruguay	1
United States\|Argentina\|Australia\|Austria\|Belgium\|Brazil\|Chile\|Czech Republic\|Denmark\|Estonia\|France\|Germany\|Greece\|Italy\|Korea, Republic of\|Netherlands\|New Zealand\|Norway\|Poland\|Puerto Rico\|Romania\|Russian Federation\|South Africa\|Spain\|Sweden\|Turkey\|Ukraine\|United Kingdom	1
United States\|Argentina\|Australia\|Austria\|Belgium\|Colombia\|France\|Germany\|Greece\|Italy\|Netherlands\|Peru\|Portugal\|Spain\|Sweden\|Taiwan\|United Kingdom\|Venezuela	1
United States\|Argentina\|Australia\|Belgium\|Brazil\|Canada\|Chile\|Croatia\|Czech Republic\|Denmark\|Estonia\|France\|Germany\|Hong Kong\|Hungary\|Israel\|Italy\|Korea, Republic of\|Netherlands\|Poland\|Portugal\|Russian Federation\|Singapore\|South Africa\|Spain\|Sweden\|Switzerland\|Taiwan\|Turkey\|Ukraine\|United Kingdom	1
United States\|Argentina\|Australia\|Belgium\|Brazil\|Canada\|Chile\|Denmark\|France\|Germany\|Italy\|Netherlands\|Peru\|Poland\|Puerto Rico\|Romania\|Singapore\|Spain\|United Kingdom	1
United States\|Argentina\|Australia\|Belgium\|Brazil\|China\|France\|Germany\|Italy\|Japan\|Korea, Republic of\|Poland\|Spain\|Taiwan\|United Kingdom	1
United States\|Argentina\|Belgium\|Brazil\|Bulgaria\|Canada\|China\|France\|Germany\|Greece\|Hungary\|India\|Israel\|Italy\|Japan\|Korea, Republic of\|Malaysia\|Mexico\|Netherlands\|Peru\|Poland\|Portugal\|Romania\|Russian Federation\|Spain\|Switzerland\|Taiwan\|Thailand\|Turkey	1
United States\|Argentina\|Belgium\|Brazil\|Canada\|Chile\|Czech Republic\|Denmark\|Finland\|France\|Germany\|Hungary\|India\|Italy\|Korea, Republic of\|Mexico\|Netherlands\|Russian Federation\|Singapore\|Slovakia\|South Africa\|Spain\|Sweden\|Taiwan\|Turkey\|United Kingdom	1
United States\|Argentina\|Belgium\|Brazil\|Chile\|Finland\|France\|Greece\|Israel\|Italy\|Mexico\|Peru\|Russian Federation\|Spain\|Turkey\|Ukraine\|United Kingdom	1
United States\|Argentina\|Estonia	1
United States\|Australia\|Austria\|Belgium\|Brazil\|Canada\|France\|Germany\|Hong Kong\|Italy\|New Zealand\|Portugal\|Slovakia\|Spain\|Sweden\|Switzerland\|Taiwan\|United Kingdom	1
United States\|Australia\|Austria\|Belgium\|Brazil\|Canada\|France\|Germany\|Japan\|Korea, Republic of\|Switzerland	1
United States\|Australia\|Austria\|Belgium\|Canada\|China\|France\|Germany\|Italy\|Japan\|Netherlands\|Poland\|Russian Federation\|Spain\|Sweden\|United Kingdom	1
United States\|Australia\|Austria\|Belgium\|Canada\|Czechia\|Denmark\|Finland\|France\|Germany\|Greece\|Italy\|Netherlands\|Norway\|Poland\|Portugal\|Russian Federation\|Slovakia\|Spain\|Sweden\|Ukraine\|United Kingdom	1
United States\|Australia\|Austria\|Belgium\|Canada\|Czechia\|Denmark\|Finland\|France\|Germany\|Hong Kong\|Hungary\|Ireland\|Italy\|Korea, Republic of\|Netherlands\|Portugal\|Singapore\|Spain\|Taiwan\|United Kingdom	1
United States\|Australia\|Austria\|Belgium\|Canada\|Finland\|France\|Japan\|Spain\|Taiwan	1
United States\|Australia\|Austria\|Brazil\|Bulgaria\|Croatia\|Czechia\|Denmark\|Finland\|France\|Greece\|Korea, Republic of\|Netherlands\|Norway\|Philippines\|Poland\|Romania\|Russian Federation\|Singapore\|Spain\|Taiwan\|Ukraine\|United Kingdom	1
United States\|Australia\|Austria\|Bulgaria\|Canada\|Czechia\|France\|Germany\|Greece\|Hong Kong\|Hungary\|Ireland\|Italy\|Japan\|Korea, Republic of\|Lithuania\|Malaysia\|New Zealand\|Poland\|Portugal\|Russian Federation\|Singapore\|Slovakia\|Spain\|Switzerland\|Taiwan\|Turkey\|Ukraine\|United Kingdom	1
United States\|Australia\|Austria\|Canada\|France\|Germany\|Italy\|Netherlands\|Poland\|Spain\|Sweden\|United Kingdom	1
United States\|Australia\|Austria\|Canada\|France\|Germany\|Italy\|Spain\|Sweden	1
United States\|Australia\|Austria\|Canada\|France\|Greece\|Indonesia\|Italy\|Korea, Republic of\|Philippines\|Singapore\|Spain\|Sweden\|Switzerland\|Thailand	1
United States\|Australia\|Austria\|France\|Germany\|Israel\|Italy\|Korea, Republic of\|Netherlands\|Singapore\|Spain\|Taiwan\|Thailand\|Turkey	1
United States\|Australia\|Belgium	1
United States\|Australia\|Belgium\|Brazil\|Bulgaria\|China\|Colombia\|Czechia\|France\|Germany\|Hong Kong\|Italy\|Japan\|Korea, Republic of\|Lebanon\|Malaysia\|Poland\|Russian Federation\|Singapore\|Spain\|Taiwan	1
United States\|Australia\|Belgium\|Brazil\|Canada\|Czechia\|France\|Germany\|Hungary\|Italy\|Netherlands\|New Zealand\|Portugal\|Slovakia\|Spain\|Sweden\|Switzerland\|Taiwan\|United Kingdom	1
United States\|Australia\|Belgium\|Brazil\|China\|Denmark\|France\|Germany\|Hungary\|Ireland\|Italy\|Japan\|Korea, Republic of\|Portugal\|Russian Federation\|Singapore\|Slovakia\|Spain\|Taiwan\|United Kingdom	1
United States\|Australia\|Belgium\|Bulgaria\|Finland\|France\|Germany\|Italy\|New Zealand\|Poland\|Spain\|Ukraine\|United Kingdom	1
United States\|Australia\|Belgium\|Canada\|Denmark\|Hungary\|Korea, Republic of\|Russian Federation\|United Kingdom	1
United States\|Australia\|Belgium\|Canada\|Estonia\|France\|Netherlands\|Spain\|United Kingdom	1
United States\|Australia\|Belgium\|Canada\|France\|Germany\|Hong Kong\|Italy\|Japan\|Singapore\|Spain\|Taiwan	1
United States\|Australia\|Belgium\|Canada\|France\|Germany\|Italy\|Japan\|Korea, Republic of\|Spain\|Taiwan\|United Kingdom	1
United States\|Australia\|Belgium\|Canada\|France\|Germany\|Italy\|Korea, Republic of\|Netherlands\|Singapore\|Spain\|Switzerland	1
United States\|Australia\|Belgium\|Canada\|France\|Germany\|Italy\|Taiwan\|United Kingdom	1
United States\|Australia\|Belgium\|Canada\|France\|Hungary\|Italy\|Korea, Republic of\|New Zealand\|Spain\|United Kingdom	1
United States\|Australia\|Belgium\|Canada\|France\|Italy\|Singapore\|Spain\|Switzerland	1
United States\|Australia\|Belgium\|Canada\|Germany\|Netherlands\|Singapore\|Spain	1
United States\|Australia\|Belgium\|Canada\|Japan\|Poland\|United Kingdom	1
United States\|Australia\|Belgium\|China\|France\|Germany\|Hong Kong\|Italy\|Japan\|Korea, Republic of\|Netherlands\|Poland\|Singapore\|Spain\|Taiwan\|United Kingdom	1
United States\|Australia\|Belgium\|Denmark\|France\|Germany\|Ireland\|Italy\|Netherlands\|Spain\|Switzerland\|United Kingdom	1
United States\|Australia\|Belgium\|France	1
United States\|Australia\|Belgium\|France\|Korea, Republic of	1
United States\|Australia\|Belgium\|France\|Netherlands\|Spain	1
United States\|Australia\|Belgium\|Italy\|Spain	1
United States\|Australia\|Brazil\|France\|Germany\|Israel\|Italy\|Korea, Republic of\|New Zealand\|Sweden\|United Kingdom	1
United States\|Australia\|Bulgaria\|Poland\|Spain\|Thailand\|Ukraine	1
United States\|Australia\|Canada\|China\|Denmark\|France\|Germany\|Ireland\|Israel\|Italy\|Japan\|Korea, Republic of\|Netherlands\|Poland\|Spain\|Sweden\|Switzerland\|United Kingdom	1
United States\|Australia\|Canada\|Denmark\|France\|Germany\|Italy\|Netherlands\|United Kingdom	1
United States\|Australia\|Canada\|Estonia\|Georgia\|India\|Korea, Republic of\|Puerto Rico\|South Africa	1
United States\|Australia\|Canada\|France\|Germany\|Hong Kong\|Israel\|Italy\|Korea, Republic of\|Netherlands\|Norway\|Singapore\|Spain\|Taiwan\|Thailand	1
United States\|Australia\|Canada\|France\|Germany\|Italy\|Japan\|Spain\|Switzerland	1
United States\|Australia\|Canada\|France\|Germany\|Italy\|Korea, Republic of\|Netherlands\|Spain\|United Kingdom	1
United States\|Australia\|Canada\|France\|Germany\|Netherlands\|Switzerland\|United Kingdom	1
United States\|Australia\|Canada\|France\|Israel\|Japan\|Korea, Republic of\|Spain\|Taiwan	1
United States\|Australia\|Canada\|France\|Japan\|Korea, Republic of\|Spain	1
United States\|Australia\|Canada\|France\|Japan\|Poland\|Taiwan\|United Kingdom	1
United States\|Australia\|Canada\|France\|Netherlands\|United Kingdom	1
United States\|Australia\|Canada\|France\|Spain	1
United States\|Australia\|Canada\|Germany\|Korea, Republic of\|Singapore	1
United States\|Australia\|Canada\|Hong Kong\|Italy\|Korea, Republic of\|Netherlands\|Poland\|Singapore\|Spain\|United Kingdom	1
United States\|Australia\|Canada\|Israel\|New Zealand\|Puerto Rico	1
United States\|Australia\|Canada\|Japan\|New Zealand\|Puerto Rico\|Saudi Arabia	1
United States\|Australia\|Canada\|Netherlands\|New Zealand\|Switzerland	1
United States\|Australia\|Canada\|New Zealand	1
United States\|Australia\|Canada\|New Zealand\|Switzerland	1
United States\|Australia\|Canada\|Switzerland	1
United States\|Australia\|Chile\|France\|Israel\|Japan\|Korea, Republic of\|New Zealand\|Poland\|Spain	1
United States\|Australia\|China\|Israel\|New Zealand\|Poland\|Russian Federation\|South Africa\|Switzerland\|United Kingdom	1
United States\|Australia\|China\|Japan\|Korea, Republic of\|New Zealand\|Taiwan	1
United States\|Australia\|China\|New Zealand\|Taiwan	1
United States\|Australia\|France\|Hong Kong\|Japan\|Korea, Republic of\|Netherlands\|Spain\|Taiwan\|United Kingdom	1
United States\|Australia\|France\|Hong Kong\|Malta\|Poland\|Russian Federation\|Ukraine	1
United States\|Australia\|France\|Italy\|Korea, Republic of\|Netherlands\|Portugal\|Spain\|Taiwan	1
United States\|Australia\|France\|Italy\|Spain\|Switzerland\|United Kingdom	1
United States\|Australia\|France\|Korea, Republic of\|Spain\|United Kingdom	1
United States\|Australia\|France\|New Zealand\|Spain\|United Kingdom	1
United States\|Australia\|France\|Taiwan	1
United States\|Australia\|Germany	1
United States\|Australia\|Hong Kong\|Korea, Republic of\|Taiwan\|Thailand	1
United States\|Australia\|Ireland\|Korea, Republic of\|United Kingdom	1
United States\|Australia\|Israel\|Korea, Republic of	1
United States\|Australia\|Italy\|Korea, Republic of\|New Zealand\|United Kingdom	1
United States\|Australia\|Korea, Republic of\|Netherlands\|Spain	1
United States\|Australia\|Netherlands	1
United States\|Australia\|Peru\|Puerto Rico	1
United States\|Australia\|Singapore	1
United States\|Australia\|Spain	1
United States\|Australia\|Spain\|United Kingdom	1
United States\|Australia\|United Kingdom	1
United States\|Austria\|Belgium\|Czechia\|Greece\|Italy\|Spain\|United Kingdom	1
United States\|Austria\|Belgium\|Denmark\|Italy\|Japan\|Spain	1
United States\|Austria\|Canada\|France\|Germany\|Italy\|Japan\|Spain\|Switzerland\|United Kingdom	1
United States\|Austria\|Denmark\|Germany\|Netherlands\|Spain\|Sweden\|United Kingdom	1
United States\|Belarus\|Belgium\|Bosnia and Herzegovina\|Brazil\|Canada\|Croatia\|Cyprus\|Egypt\|France\|Germany\|Greece\|Hungary\|Israel\|Italy\|Korea, Republic of\|Netherlands\|New Zealand\|Portugal\|Romania\|Russian Federation\|Serbia\|South Africa\|Spain\|United Kingdom	1
United States\|Belgium\|Bulgaria\|Croatia\|North Macedonia\|Serbia\|Slovakia\|Slovenia	1
United States\|Belgium\|Canada\|Czech Republic\|Finland\|France\|Germany\|Greece\|Israel\|Slovakia\|Switzerland\|Turkey\|United Kingdom	1
United States\|Belgium\|Canada\|Czechia\|France\|Greece\|Italy\|Netherlands\|Spain\|Taiwan	1
United States\|Belgium\|Canada\|Denmark\|Italy\|Netherlands\|Spain	1
United States\|Belgium\|Canada\|France\|Italy\|Spain\|Switzerland	1
United States\|Belgium\|Canada\|France\|Korea, Republic of\|Spain\|Taiwan	1
United States\|Belgium\|Canada\|Italy\|Spain	1
United States\|Belgium\|Canada\|Spain	1
United States\|Belgium\|Canada\|Spain\|Switzerland	1
United States\|Belgium\|China\|France\|India\|Mexico\|Russian Federation	1
United States\|Belgium\|Czechia\|France\|Germany\|Korea, Republic of\|Poland\|Taiwan\|United Kingdom	1
United States\|Belgium\|Czechia\|Israel	1
United States\|Belgium\|Denmark\|Netherlands\|Russian Federation\|Spain\|United Kingdom	1
United States\|Belgium\|Denmark\|Netherlands\|Sweden	1
United States\|Belgium\|Finland\|France\|Italy\|Japan\|Korea, Republic of\|Taiwan	1
United States\|Belgium\|Finland\|France\|Puerto Rico\|Spain	1
United States\|Belgium\|France\|Germany\|Italy\|Korea, Republic of\|Netherlands\|Poland\|Spain\|United Kingdom	1
United States\|Belgium\|France\|Germany\|Italy\|Portugal\|Spain\|United Kingdom	1
United States\|Belgium\|France\|Germany\|Italy\|Spain	1
United States\|Belgium\|France\|Germany\|Italy\|Spain\|Sweden\|Switzerland\|United Kingdom	1
United States\|Belgium\|France\|Hong Kong\|Korea, Republic of\|Spain\|Taiwan	1
United States\|Belgium\|France\|Japan\|Spain\|United Kingdom	1
United States\|Belgium\|France\|Korea, Republic of\|Spain\|United Kingdom	1
United States\|Belgium\|France\|Spain\|United Kingdom	1
United States\|Belgium\|Germany\|Hungary\|Korea, Republic of\|United Kingdom	1
United States\|Belgium\|Germany\|Korea, Republic of\|Singapore\|Spain	1
United States\|Belgium\|Italy\|Japan\|Korea, Republic of\|Spain	1
United States\|Belgium\|Netherlands	1
United States\|Belgium\|Netherlands\|Spain\|United Kingdom	1
United States\|Belgium\|Spain\|United Kingdom	1
United States\|Brazil\|France\|Israel\|Italy\|Netherlands\|Portugal\|Singapore\|Spain\|United Kingdom	1
United States\|Brazil\|France\|Italy\|Korea, Republic of\|Russian Federation\|Ukraine	1
United States\|Bulgaria\|Czechia\|Germany\|Hungary\|Mexico\|Poland\|Puerto Rico\|Romania\|United Kingdom	1
United States\|Bulgaria\|Denmark\|France\|Italy\|Spain\|United Kingdom	1
United States\|Canada\|China\|France\|Germany\|Hong Kong\|Italy\|Taiwan	1
United States\|Canada\|Czechia\|France\|Hungary\|Slovakia\|Spain	1
United States\|Canada\|Denmark\|Finland\|Germany\|Italy\|Spain\|United Kingdom	1
United States\|Canada\|Denmark\|France\|Italy\|Japan\|Netherlands\|Singapore\|Spain\|United Kingdom	1
United States\|Canada\|Denmark\|France\|Netherlands\|Spain	1
United States\|Canada\|Denmark\|Netherlands\|Spain\|Switzerland	1
United States\|Canada\|Finland\|France\|Germany\|Italy\|Korea, Republic of\|Spain	1
United States\|Canada\|France	1
United States\|Canada\|France\|Germany\|Israel\|Italy\|Spain\|United Kingdom	1
United States\|Canada\|France\|Germany\|Italy\|Korea, Republic of\|Netherlands\|United Kingdom	1
United States\|Canada\|France\|Germany\|Italy\|Poland\|Spain	1
United States\|Canada\|France\|Italy\|Poland	1
United States\|Canada\|France\|Italy\|Spain\|Switzerland	1
United States\|Canada\|France\|Italy\|Spain\|Switzerland\|United Kingdom	1
United States\|Canada\|France\|Korea, Republic of\|Spain	1
United States\|Canada\|France\|Netherlands	1
United States\|Canada\|France\|Spain	1
United States\|Canada\|Germany\|Netherlands\|Singapore\|Spain\|Switzerland	1
United States\|Canada\|Israel	1
United States\|Canada\|Italy\|Japan\|Korea, Republic of\|Netherlands\|Singapore\|Switzerland\|Taiwan	1
United States\|Canada\|Italy\|Japan\|Korea, Republic of\|Portugal\|Spain\|Taiwan\|United Kingdom	1
United States\|Canada\|Italy\|Spain	1
United States\|Canada\|Italy\|United Kingdom	1
United States\|Canada\|Japan\|Taiwan	1
United States\|Canada\|Korea, Republic of\|Poland\|Taiwan\|United Kingdom	1
United States\|Canada\|Korea, Republic of\|Taiwan	1
United States\|Canada\|Netherlands	1
United States\|Canada\|Netherlands\|Poland\|Spain	1
United States\|Canada\|Netherlands\|Russian Federation	1
United States\|Canada\|Netherlands\|Slovakia\|United Kingdom	1
United States\|Canada\|Norway\|Spain\|Switzerland	1
United States\|Canada\|Russian Federation\|Ukraine	1
United States\|Canada\|Singapore	1
United States\|Canada\|Spain\|Switzerland	1
United States\|Canada\|Switzerland	1
United States\|China\|Italy\|Japan\|Korea, Republic of\|Russian Federation\|Taiwan	1
United States\|Cyprus	1
United States\|Czechia\|Italy\|Korea, Republic of\|Netherlands\|Russian Federation\|Spain\|Thailand\|Turkey	1
United States\|Denmark\|Finland\|France\|Japan\|Korea, Republic of\|Spain	1
United States\|Denmark\|France\|Germany\|Spain\|United Kingdom	1
United States\|Denmark\|France\|Italy\|Japan\|Korea, Republic of\|Spain\|Switzerland\|United Kingdom	1
United States\|Denmark\|Germany	1
United States\|Denmark\|Germany\|Japan	1
United States\|Denmark\|Italy\|Spain	1
United States\|Denmark\|Netherlands\|Switzerland	1
United States\|Denmark\|United Kingdom	1
United States\|France\|Germany\|Hong Kong\|Hungary\|Italy\|Netherlands\|Spain\|United Kingdom	1
United States\|France\|Germany\|Italy\|Netherlands\|United Kingdom	1
United States\|France\|Germany\|Italy\|Norway\|United Kingdom	1
United States\|France\|Germany\|Japan\|Netherlands\|Singapore\|Spain\|Taiwan	1
United States\|France\|Germany\|Singapore\|Switzerland	1
United States\|France\|Germany\|Spain	1
United States\|France\|Israel\|Spain\|Taiwan	1
United States\|France\|Italy	1
United States\|France\|Italy\|Netherlands\|Spain\|Switzerland	1
United States\|France\|Italy\|United Kingdom	1
United States\|France\|Japan\|Netherlands	1
United States\|France\|Japan\|Puerto Rico\|Spain\|Taiwan	1
United States\|France\|Korea, Republic of\|Spain	1
United States\|France\|Korea, Republic of\|Spain\|United Kingdom	1
United States\|France\|Netherlands\|Spain	1
United States\|France\|Netherlands\|United Kingdom	1
United States\|France\|Singapore\|Spain\|Taiwan	1
United States\|France\|Slovakia	1
United States\|France\|Spain	1
United States\|France\|Spain\|Switzerland	1
United States\|Germany\|Netherlands	1
United States\|Germany\|Netherlands\|Spain\|United Kingdom	1
United States\|Germany\|New Zealand	1
United States\|Germany\|Spain\|United Kingdom	1
United States\|Germany\|United Kingdom	1
United States\|Hungary\|Israel\|Italy\|Spain	1
United States\|India	1
United States\|Israel	1
United States\|Israel\|Italy\|Japan\|Singapore\|Spain\|Taiwan	1
United States\|Israel\|Netherlands\|Spain	1
United States\|Israel\|United Kingdom	1
United States\|Italy\|Japan\|Korea, Republic of	1
United States\|Italy\|Korea, Republic of	1
United States\|Italy\|Korea, Republic of\|Spain	1
United States\|Italy\|Netherlands\|Singapore\|Spain	1
United States\|Italy\|Puerto Rico	1
United States\|Italy\|Spain	1
United States\|Italy\|Spain\|United Kingdom	1
United States\|Japan\|Korea, Republic of\|Spain	1
United States\|Japan\|Netherlands\|Spain	1
United States\|Netherlands\|New Zealand\|Australia\|Canada\|Puerto Rico\|Switzerland	1
United States\|Netherlands\|Spain\|United Kingdom	1
United States\|Netherlands\|Sweden\|Switzerland\|United Kingdom	1
United States\|Netherlands\|United Kingdom	1
United States\|Norway	1
United States\|Norway\|Spain	1
United States\|Poland\|Spain	1
United States\|Puerto Rico\|Saudi Arabia	1
United States\|Switzerland	1

Sites per Study

Site_count	Study_Count
1	1882
2	365
3	283
4	153
5	124
6	92
7	60
8	68
9	47
10	46
11	42
12	44
13	23
14	22
15	31
16	19
17	16
18	17
19	12
20	19
21	17
22	15
23	11
24	14
25	6
26	6
27	13
28	7
29	7
30	7
31	4
32	4
33	6
34	5
35	3
36	2
37	4
38	3
39	7
40	3
41	2
42	1
43	6
44	1
47	3
49	5
50	1
51	1
52	2
53	2
54	1
55	3
56	3
57	3
58	2
59	5
61	3
62	1
63	1
64	1
65	2
66	2
68	1
69	1
71	1
72	2
74	1
75	2
76	2
80	1
81	1
82	1
83	1
86	1
87	1
88	1
90	1
92	1
94	2
95	1
96	1
97	1
98	2
103	2
105	3
106	2
107	2
109	3
110	2
111	2
112	2
113	1
114	1
115	2
118	2
130	1
131	1
137	1
142	1
143	1
145	1
153	1
159	1
160	1
163	1
165	1
167	1
169	1
177	2
179	1
187	1
188	1
196	1
204	1
220	1
221	1
223	1
226	1
251	1
262	1
281	1
302	1
309	1
317	1
319	1
326	1
330	1
366	1
371	1
382	1
394	1
405	1
434	1
472	1
499	1
504	1
508	1
516	1
559	1
721	1
937	1
1328	1

Phase

Phase	Study_Count
Phase 1	1815
Phase 2	650
N/A	536
Phase 1/Phase 2	356
Phase 3	167
Phase 4	52
Early Phase 1	44
Phase 2/Phase 3	38

Number of Arms

Number_of_Arms	Count_of_Studies
1	1849
2	851
3	242
4	143
5	62
6	37
7	31
8	12
9	18
10	8
11	4
12	9
13	2
14	2
16	1
17	1
18	1
19	1
27	1
28	1
37	1
NA	381

Number of Updates

Count of Versions	Count of Studies
1	183
2	246
3	308
4	260
5	210
6	220
7	201
8	183
9	142
10	156
11	139
12	122
13	98
14	101
15	84
16	87
17	67
18	64
19	43
20	51
21	42
22	27
23	33
24	41
25	28
26	29
27	15
28	33
29	21
30	31
31	15
32	16
33	21
34	12
35	15
36	18
37	9
38	7
39	8
40	4
41	6
42	7
43	8
44	6
45	8
46	13
47	9
48	7
49	8
50	3
51	5
52	7
53	7
54	2
55	4
56	4
57	4
58	1
59	4
60	2
61	3
62	1
63	7
64	7
65	1
66	3
67	6
68	1
69	4
70	6
71	4
72	2
73	1
74	5
77	1
78	1
79	3
80	5
81	2
82	3
84	2
85	5
86	2
88	3
90	1
91	1
93	1
94	3
96	2
97	1
98	3
99	1
100	2
102	2
103	1
106	1
108	2
109	1
111	1
112	1
115	1
116	1
118	1
119	1
124	1
125	1
128	1
132	1
134	1
138	1
139	1
141	1
143	1
149	1
154	1
156	1
157	1
159	1
170	1
173	1
182	1
185	1
186	1
206	1
208	1
209	1
211	1
213	1
214	1
215	1
216	1
217	2
219	1
224	1
231	1
234	1
240	1
242	1
250	1
270	1
333	1
412	1
415	1
489	1
500	1
513	1
553	1
565	1
572	1
879	1

Update History Change Type

Change Type	Count_of_Changes	Count_of_Studies	ratio
Study Status	57507	3475	16.548777
Contacts/Locations	27782	3174	8.752993
Recruitment Status	6330	3055	2.072013
Study Design	5738	2576	2.227485
Eligibility	5303	2107	2.516849
Arms	5054	2056	2.458171
Interventions	5054	2056	2.458171
Study Description	4407	1741	2.531304
Study Identification	4125	1908	2.161950
Outcome Measures	3935	1957	2.010731
None (earliest Version on record)	3658	3658	1.000000
Conditions	3261	1373	2.375091
Sponsor/Collaborators	2929	1659	1.765521
Oversight	2560	1728	1.481481
References	1226	741	1.654521
More Information	602	226	2.663717
IPDSharing	488	407	1.199017
Results	376	376	1.000000
Results Submission Events	140	140	1.000000
Baseline Characteristics	116	97	1.195876
Documents	106	103	1.029126
Participant Flow	89	73	1.219178
Reported Adverse Events	77	66	1.166667
2020 Outcome Measures	1	1	1.000000
Quality Control Review has not concludedReturned: February 15	1	1	1.000000

Enrollment Metrics by Phase

Measure	Early.Phase.1	N.A	Phase.1	Phase.1.Phase.2	Phase.2	Phase.2.Phase.3	Phase.3	Phase.4
Min.	1.0000	4.0000	1.00000	2.0000	1.0000	9.0000	12.0000	10.0000
1st Qu.	10.0000	30.0000	23.00000	37.0000	32.0000	54.7500	131.5000	48.2500
Median	20.0000	72.0000	37.00000	72.0000	53.0000	115.0000	280.0000	89.0000
Mean	236.4091	281.7533	59.07579	112.9942	111.9857	475.1316	517.5723	343.8654
3rd Qu.	43.7500	201.0000	65.00000	144.0000	100.0000	248.2500	555.0000	260.5000
Max.	8800.0000	15431.0000	1758.00000	1131.0000	6452.0000	10838.0000	7466.0000	8000.0000

Trial Group Type

group_type	Group_Count
Experimental	5434
Active Comparator	458
NA	381
Other	182
No Intervention	116
Placebo Comparator	97
Sham Comparator	17

Intervention Model

intervention_model	Study_Count
Single Group Assignment	2166
Parallel Assignment	1024
Sequential Assignment	209
NA	182
Crossover Assignment	64
Factorial Assignment	13

Primary Purpose

primary_purpose	Study_Count
Treatment	2980
Supportive Care	238
Diagnostic	131
Prevention	91
Other	80
NA	45
Health Services Research	31
Basic Science	29
Screening	26
Device Feasibility	7

Observational Studies

Studies by Country

Country	Study_Count
United States	214
France	38
China	34
NA	23
Italy	18
Canada	13
Korea, Republic of	9
Netherlands	9
United Kingdom	9
United States\|Canada	9
Egypt	8
Taiwan	8
Norway	7
Belgium	6
Denmark	6
Spain	6
Germany	5
Hong Kong	4
Poland	4
Sweden	4
Brazil	3
Finland	3
Switzerland	3
Czech Republic	2
India	2
Singapore	2
Turkey	2
United States\|Australia\|Canada\|New Zealand\|Puerto Rico\|Switzerland	2
Argentina\|Austria\|Czechia\|Denmark\|France\|Italy\|Luxembourg\|Mexico\|Netherlands\|Singapore\|Spain\|Switzerland\|Taiwan	1
Argentina\|Brazil\|Mexico	1
Australia\|Canada\|Czech Republic\|Italy\|Netherlands	1
Austria	1
Austria\|Belgium\|Germany	1
Austria\|Belgium\|Germany\|Italy	1
Austria\|Croatia	1
Austria\|Germany	1
Belgium\|Germany	1
Cambodia	1
Canada\|Denmark\|United Kingdom	1
Croatia	1
Czechia\|Germany\|Israel\|Italy\|Spain\|United Kingdom	1
Denmark\|Sweden	1
France\|Germany\|Netherlands	1
Germany\|Greece\|Italy	1
Germany\|Italy	1
Germany\|Serbia\|United Kingdom	1
Hungary	1
Ireland	1
Israel	1
Italy\|Romania\|Russian Federation\|Serbia\|Spain\|Turkey	1
Italy\|Spain\|Sweden	1
Italy\|United States\|Greece\|Israel\|Netherlands\|Norway\|Poland\|Portugal\|Spain\|United Kingdom	1
Japan	1
Pakistan	1
Romania	1
United States\|Australia\|Canada	1
United States\|Australia\|Canada\|New Zealand\|Puerto Rico	1
United States\|Australia\|Canada\|New Zealand\|Puerto Rico\|Saudi Arabia	1
United States\|Australia\|Canada\|Puerto Rico\|Switzerland	1
United States\|Austria\|Belgium\|France\|Japan\|Poland	1
United States\|Canada\|France\|Germany\|Italy\|Spain\|United Kingdom	1
United States\|Canada\|Hungary	1
United States\|Canada\|Nigeria	1
United States\|Canada\|Puerto Rico\|Switzerland	1
United States\|Canada\|Spain\|United Kingdom	1
United States\|China\|India\|Japan\|Netherlands\|Sweden	1
United States\|Colombia\|Mexico\|Peru\|Puerto Rico	1
United States\|Denmark\|France\|Germany\|Italy\|Spain\|United Kingdom	1
United States\|Denmark\|India\|Portugal\|South Africa	1
United States\|Finland\|Iceland\|Sweden	1
United States\|France\|Germany\|New Zealand\|Switzerland\|United Kingdom	1
United States\|Puerto Rico	1
United States\|Taiwan	1

Sites per Study

Site_count	Study_Count
1	338
2	31
3	19
4	13
5	7
6	9
7	6
8	7
9	1
10	6
11	3
12	1
13	3
14	2
15	4
16	1
17	2
18	1
19	3
20	2
21	1
22	1
23	2
25	1
26	2
27	1
28	2
29	1
30	1
31	1
33	1
42	2
46	1
48	1
53	1
55	1
61	1
66	1
70	1
72	1
81	1
111	1
138	1
144	1
156	1
184	1
185	1
187	2
192	1
228	1
272	1
280	1
381	1
523	1

Number of Updates

Count of Versions	Count of Studies
1	69
2	80
3	64
4	45
5	29
6	26
7	26
8	19
9	18
10	16
11	14
12	4
13	4
14	7
15	8
16	4
17	3
18	3
20	6
21	1
23	2
25	1
27	2
28	2
29	1
31	1
34	1
40	2
41	1
44	1
46	1
47	1
48	1
49	1
50	1
60	1
61	1
64	3
65	1
66	1
73	1
75	2
76	1
83	1
86	1
94	2
98	1
101	1
108	1
113	1
116	1
122	2
138	2
146	1
165	1
185	1
202	1
214	1
224	1
232	1
253	1
404	1

Update History Change Type

Change Type	Count_of_Changes	Count_of_Studies	ratio
Study Status	6701	429	15.620047
Contacts/Locations	3052	332	9.192771
Study Description	815	167	4.880240
Study Design	573	291	1.969072
None (earliest Version on record)	498	498	1.000000
Recruitment Status	473	290	1.631034
Eligibility	459	198	2.318182
Study Identification	264	157	1.681529
Outcome Measures	254	157	1.617834
Sponsor/Collaborators	254	170	1.494118
Conditions	230	117	1.965812
Groups	224	144	1.555556
Interventions	224	144	1.555556
Oversight	168	132	1.272727
References	132	78	1.692308
IPDSharing	35	34	1.029412
More Information	9	3	3.000000
Results	7	7	1.000000
Baseline Characteristics	3	2	1.500000
Documents	3	3	1.000000
Participant Flow	2	2	1.000000
Reported Adverse Events	2	2	1.000000
Results Submission Events	2	2	1.000000

Enrollment Metrics

Measure	Observational
Min	1.000
1st Qu	80.000
Median	204.000
Mean	9650.658
3rd Qu	849.000
Max	1600000.000

Observation Model

observational_model	Study_Count
Cohort	258
Case-Only	106
Case-Control	47
Other	33
NA	32
Case Control	10
Family-Based	6
Ecologic or Community	3
Case-Crossover	2
Case Control, Natural History	1

Time Perspective

time_perspective	Study_Count
Prospective	341
Retrospective	76
Cross-Sectional	29
NA	28
Other	24

Registries

Studies by Country

Country	Study_Count
United States	17
China	5
France	5
Germany	3
Spain	3
Brazil	2
Korea, Republic of	2
Thailand	2
United Kingdom	2
Austria	1
Belgium	1
Canada	1
Colombia	1
Denmark	1
Greece	1
Israel	1
Italy	1
NA	1
Netherlands	1
Norway	1
Saudi Arabia	1
Taiwan	1
Turkey	1
United States\|Australia	1
United States\|Canada\|Germany\|Israel	1

Sites per Study

Site_count	Study_Count
1	39
2	3
3	3
4	2
5	1
7	1
10	1
11	1
15	1
16	1
17	1
21	1
37	1
75	1

Number of Updates

Count of Versions	Count of Studies
1	11
2	12
3	11
4	6
5	5
6	4
7	2
8	1
12	1
13	1
16	1
20	1
26	1

Update History Change Type

Change Type	Count_of_Changes	Count_of_Studies	ratio
Study Status	193	46	4.195652
Contacts/Locations	75	36	2.083333
None (earliest Version on record)	57	57	1.000000
Study Design	41	25	1.640000
Recruitment Status	32	25	1.280000
Outcome Measures	26	15	1.733333
Study Identification	26	13	2.000000
Eligibility	24	15	1.600000
Study Description	24	16	1.500000
Conditions	22	10	2.200000
Sponsor/Collaborators	18	9	2.000000
References	13	6	2.166667
Groups	12	8	1.500000
Interventions	12	8	1.500000
Oversight	10	9	1.111111
IPDSharing	9	6	1.500000

Enrollment Metrics

Measure	Registries
Min	20.00
1st Qu	171.00
Median	500.00
Mean	20509.84
3rd Qu	4000.00
Max	999999.00

Registry Model

observational_model	Study_Count
Cohort	38
Case-Only	8
Other	8
Case Control	2
NA	1

Time Perspective

time_perspective	Study_Count
Prospective	46
Other	7
Cross-Sectional	4

Follow-up

target_duration	Study_Count
1 Year	11
10 Years	7
5 Years	7
2 Years	6
12 Months	5
1 Day	3
24 Months	2
3 Years	2
4 Years	2
6 Months	2
1 Month	1
1 Week	1
100 Years	1
20 Years	1
30 Years	1
48 Months	1
60 Months	1
7 Days	1
80 Years	1
99 Years	1

intervention_type	Study_Count
Drug	2056
Biological	228
Drug\|Other	158
Procedure	132
Other	115
Device	96
Biological\|Drug	95
Behavioral	76
Drug\|Procedure	63
Drug\|placebo	57
Radiation	51
Drug\|Radiation	42
Other\|Procedure	34
Biological\|Drug\|Other	32
Biological\|Other	29
Drug\|Procedure\|Radiation	27
Biological\|Drug\|Procedure	22
Behavioral\|Other	21
Drug\|Other\|Procedure	20
Device\|Procedure	19
Device\|Drug	17
Genetic	15
Dietary Supplement	14
Other\|Radiation	14
Procedure\|Radiation	14
Drug\|Other\|placebo	10
Drug\|Other\|Procedure\|Radiation	10
Combination Product	9
Behavioral\|Drug	8
Biological\|Drug\|Procedure\|Radiation	8
Device\|Drug\|Procedure	8
Diagnostic Test	8
Dietary Supplement\|Drug	8
Behavioral\|Other\|Procedure	7
Biological\|Drug\|Radiation	6
Biological\|Other\|Procedure	6
Device\|Other	6
Drug\|Genetic\|Other	6
Other\|Procedure\|Radiation	6
Biological\|Drug\|Other\|Procedure\|Radiation	5
Biological\|Procedure	4
Combination Product\|Drug	4
Device\|Other\|Procedure	4
Drug\|Genetic\|Other\|Procedure	4
Behavioral\|Device	3
Biological\|Drug\|Other\|Procedure	3
Biological\|placebo	3
Device\|Procedure\|Radiation	3
Device\|Radiation	3
Drug\|Genetic	3
Drug\|Other\|placebo\|Procedure	3
Behavioral\|Drug\|Other	2
Behavioral\|Drug\|placebo	2
Behavioral\|Radiation	2
Biological\|Device	2
Biological\|Device\|Drug\|Procedure	2
Biological\|Drug\|placebo	2
Biological\|Other\|Radiation	2
Device\|Drug\|Radiation	2
Dietary Supplement\|placebo	2
Drug\|Other\|Radiation	2
Drug\|placebo\|Procedure	2
Behavioral\|Device\|Drug\|placebo	1
Behavioral\|Device\|Other	1
Behavioral\|Device\|Procedure	1
Behavioral\|Dietary Supplement\|Other\|Procedure	1
Behavioral\|Drug\|Other\|placebo	1
Behavioral\|Drug\|Procedure	1
Behavioral\|placebo	1
Behavioral\|Procedure	1
Behavioral\|Procedure\|Radiation	1
Biological\|Combination Product	1
Biological\|Combination Product\|Drug\|Other	1
Biological\|Device\|Drug	1
Biological\|Device\|Drug\|Other	1
Biological\|Device\|Other	1
Biological\|Device\|placebo	1
Biological\|Device\|Procedure	1
Biological\|Dietary Supplement\|Drug\|Other\|placebo\|Procedure	1
Biological\|Genetic\|Other	1
Biological\|Genetic\|Other\|Procedure	1
Biological\|Other\|placebo	1
Biological\|Other\|Procedure\|Radiation	1
Biological\|placebo\|Procedure	1
Biological\|Radiation	1
Combination Product\|Other\|Procedure	1
Combination Product\|Procedure	1
Device\|Drug\|Genetic\|Procedure	1
Device\|Drug\|Other	1
Device\|Other\|Procedure\|Radiation	1
Device\|placebo	1
Diagnostic Test\|Drug\|Other	1
Diagnostic Test\|Drug\|Procedure	1
Diagnostic Test\|Drug\|Procedure\|Radiation	1
Diagnostic Test\|Other	1
Dietary Supplement\|Drug\|Other	1
Dietary Supplement\|Other	1
Dietary Supplement\|Other\|placebo	1
Dietary Supplement\|Other\|Procedure	1
Drug\|Genetic\|Other\|Procedure\|Radiation	1
Drug\|Genetic\|Radiation	1
Other\|placebo	1
placebo\|Procedure	1

Count of Versions	Count of Studies
1	183
2	246
3	308
4	260
5	210
6	220
7	201
8	183
9	142
10	156
11	139
12	122
13	98
14	101
15	84
16	87
17	67
18	64
19	43
20	51
21	42
22	27
23	33
24	41
25	28
26	29
27	15
28	33
29	21
30	31
31	15
32	16
33	21
34	12
35	15
36	18
37	9
38	7
39	8
40	4
41	6
42	7
43	8
44	6
45	8
46	13
47	9
48	7
49	8
50	3
51	5
52	7
53	7
54	2
55	4
56	4
57	4
58	1
59	4
60	2
61	3
62	1
63	7
64	7
65	1
66	3
67	6
68	1
69	4
70	6
71	4
72	2
73	1
74	5
77	1
78	1
79	3
80	5
81	2
82	3
84	2
85	5
86	2
88	3
90	1
91	1
93	1
94	3
96	2
97	1
98	3
99	1
100	2
102	2
103	1
106	1
108	2
109	1
111	1
112	1
115	1
116	1
118	1
119	1
124	1
125	1
128	1
132	1
134	1
138	1
139	1
141	1
143	1
149	1
154	1
156	1
157	1
159	1
170	1
173	1
182	1
185	1
186	1
206	1
208	1
209	1
211	1
213	1
214	1
215	1
216	1
217	2
219	1
224	1
231	1
234	1
240	1
242	1
250	1
270	1
333	1
412	1
415	1
489	1
500	1
513	1
553	1
565	1
572	1
879	1

Site_count	Study_Count
1	338
2	31
3	19
4	13
5	7
6	9
7	6
8	7
9	1
10	6
11	3
12	1
13	3
14	2
15	4
16	1
17	2
18	1
19	3
20	2
21	1
22	1
23	2
25	1
26	2
27	1
28	2
29	1
30	1
31	1
33	1
42	2
46	1
48	1
53	1
55	1
61	1
66	1
70	1
72	1
81	1
111	1
138	1
144	1
156	1
184	1
185	1
187	2
192	1
228	1
272	1
280	1
381	1
523	1

Count of Versions	Count of Studies
1	69
2	80
3	64
4	45
5	29
6	26
7	26
8	19
9	18
10	16
11	14
12	4
13	4
14	7
15	8
16	4
17	3
18	3
20	6
21	1
23	2
25	1
27	2
28	2
29	1
31	1
34	1
40	2
41	1
44	1
46	1
47	1
48	1
49	1
50	1
60	1
61	1
64	3
65	1
66	1
73	1
75	2
76	1
83	1
86	1
94	2
98	1
101	1
108	1
113	1
116	1
122	2
138	2
146	1
165	1
185	1
202	1
214	1
224	1
232	1
253	1
404	1

Count of Versions	Count of Studies
1	183
2	246
3	308
4	260
5	210
6	220
7	201
8	183
9	142
10	156
11	139
12	122
13	98
14	101
15	84
16	87
17	67
18	64
19	43
20	51
21	42
22	27
23	33
24	41
25	28
26	29
27	15
28	33
29	21
30	31
31	15
32	16
33	21
34	12
35	15
36	18
37	9
38	7
39	8
40	4
41	6
42	7
43	8
44	6
45	8
46	13
47	9
48	7
49	8
50	3
51	5
52	7
53	7
54	2
55	4
56	4
57	4
58	1
59	4
60	2
61	3
62	1
63	7
64	7
65	1
66	3
67	6
68	1
69	4
70	6
71	4
72	2
73	1
74	5
77	1
78	1
79	3
80	5
81	2
82	3
84	2
85	5
86	2
88	3
90	1
91	1
93	1
94	3
96	2
97	1
98	3
99	1
100	2
102	2
103	1
106	1
108	2
109	1
111	1
112	1
115	1
116	1
118	1
119	1
124	1
125	1
128	1
132	1
134	1
138	1
139	1
141	1
143	1
149	1
154	1
156	1
157	1
159	1
170	1
173	1
182	1
185	1
186	1
206	1
208	1
209	1
211	1
213	1
214	1
215	1
216	1
217	2
219	1
224	1
231	1
234	1
240	1
242	1
250	1
270	1
333	1
412	1
415	1
489	1
500	1
513	1
553	1
565	1
572	1
879	1

Site_count	Study_Count
1	338
2	31
3	19
4	13
5	7
6	9
7	6
8	7
9	1
10	6
11	3
12	1
13	3
14	2
15	4
16	1
17	2
18	1
19	3
20	2
21	1
22	1
23	2
25	1
26	2
27	1
28	2
29	1
30	1
31	1
33	1
42	2
46	1
48	1
53	1
55	1
61	1
66	1
70	1
72	1
81	1
111	1
138	1
144	1
156	1
184	1
185	1
187	2
192	1
228	1
272	1
280	1
381	1
523	1

Count of Versions	Count of Studies
1	69
2	80
3	64
4	45
5	29
6	26
7	26
8	19
9	18
10	16
11	14
12	4
13	4
14	7
15	8
16	4
17	3
18	3
20	6
21	1
23	2
25	1
27	2
28	2
29	1
31	1
34	1
40	2
41	1
44	1
46	1
47	1
48	1
49	1
50	1
60	1
61	1
64	3
65	1
66	1
73	1
75	2
76	1
83	1
86	1
94	2
98	1
101	1
108	1
113	1
116	1
122	2
138	2
146	1
165	1
185	1
202	1
214	1
224	1
232	1
253	1
404	1

neoplasms

Study Counts

Studies over Time

Interventional Trials

Intervention Type

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Studies by Country

Sites per Study

Phase

Number of Arms

Number of Updates

Update History Change Type

Enrollment Metrics by Phase

Trial Group Type

Intervention Model

Primary Purpose

Observational Studies

Studies by Country

Sites per Study

Number of Updates

Update History Change Type

Enrollment Metrics

Observation Model

Time Perspective

Registries

Studies by Country

Sites per Study

Number of Updates

Update History Change Type

Enrollment Metrics

Registry Model

Time Perspective

Follow-up

Count of Versions	Count of Studies
1	183
2	246
3	308
4	260
5	210
6	220
7	201
8	183
9	142
10	156
11	139
12	122
13	98
14	101
15	84
16	87
17	67
18	64
19	43
20	51
21	42
22	27
23	33
24	41
25	28
26	29
27	15
28	33
29	21
30	31
31	15
32	16
33	21
34	12
35	15
36	18
37	9
38	7
39	8
40	4
41	6
42	7
43	8
44	6
45	8
46	13
47	9
48	7
49	8
50	3
51	5
52	7
53	7
54	2
55	4
56	4
57	4
58	1
59	4
60	2
61	3
62	1
63	7
64	7
65	1
66	3
67	6
68	1
69	4
70	6
71	4
72	2
73	1
74	5
77	1
78	1
79	3
80	5
81	2
82	3
84	2
85	5
86	2
88	3
90	1
91	1
93	1
94	3
96	2
97	1
98	3
99	1
100	2
102	2
103	1
106	1
108	2
109	1
111	1
112	1
115	1
116	1
118	1
119	1
124	1
125	1
128	1
132	1
134	1
138	1
139	1
141	1
143	1
149	1
154	1
156	1
157	1
159	1
170	1
173	1
182	1
185	1
186	1
206	1
208	1
209	1
211	1
213	1
214	1
215	1
216	1
217	2
219	1
224	1
231	1
234	1
240	1
242	1
250	1
270	1
333	1
412	1
415	1
489	1
500	1
513	1
553	1
565	1
572	1
879	1

Site_count	Study_Count
1	338
2	31
3	19
4	13
5	7
6	9
7	6
8	7
9	1
10	6
11	3
12	1
13	3
14	2
15	4
16	1
17	2
18	1
19	3
20	2
21	1
22	1
23	2
25	1
26	2
27	1
28	2
29	1
30	1
31	1
33	1
42	2
46	1
48	1
53	1
55	1
61	1
66	1
70	1
72	1
81	1
111	1
138	1
144	1
156	1
184	1
185	1
187	2
192	1
228	1
272	1
280	1
381	1
523	1

Count of Versions	Count of Studies
1	69
2	80
3	64
4	45
5	29
6	26
7	26
8	19
9	18
10	16
11	14
12	4
13	4
14	7
15	8
16	4
17	3
18	3
20	6
21	1
23	2
25	1
27	2
28	2
29	1
31	1
34	1
40	2
41	1
44	1
46	1
47	1
48	1
49	1
50	1
60	1
61	1
64	3
65	1
66	1
73	1
75	2
76	1
83	1
86	1
94	2
98	1
101	1
108	1
113	1
116	1
122	2
138	2
146	1
165	1
185	1
202	1
214	1
224	1
232	1
253	1
404	1